Pre-prints:

• Bergeron JRCB, Kollman JM (2023). A family of bacterial actin homologues forms a 3-stranded tubular structure. BioRXiv 2023.11. 07.565980
  

Publications:

• Wotherspoon, P., Johnston, H., Hardy, D.J. et al. Structure of the MlaC-MlaD complex reveals molecular basis of periplasmic phospholipid transport. Nat Commun 15, 6394 (2024).

• Gibson KH, Botting JM, Al-Otaibi N, Maitre K, Bergeron J, Starai VJ, Hoover TR (2023). Control of the flagellation pattern in Helicobacter pylori by FlhF and FlhG. J Bacteriol. 205 (9): e0011023.
  

• Cassin EK, Araujo-Hernandez SA, Baughn DS, Londono MC, Rodriguez DQ, Al-Otaibi NS, Picard A, Bergeron JRC, Tseng BS (2023). OprF Impacts Pseudomonas aeruginosa Biofilm Matrix eDNA Levels in a Nutrient-Dependent Manner. J Bacteriol. 205 (7): e0008023.
  
  
• Harrison MA, Fsarthing RJ, Allen N, Birchall K, Bond M, Kaur H, Wren BW, Bergeron JRC, Dawson L (2023). Identification of novel p-cresol inhibitors that reduce Clostridioides difficile’s ability to compete with species of the gut microbiome. Scientific reports, 13 (1): 9492.

• Evans SL, Al-Hazeem MMJ, Mann D, Smetacek N, Beavil AJ, Sun Y, Chen T, Dykes GF, Liu LN, Bergeron JRC (2023). Single-particle cryo-EM analysis of the shell architecture and internal organization of an intact α-carboxysome. Structure, 31 (6): 677-688.

• Al-Otibi NS, Bergeron JRC (2022). Structure and assembly of the bacterial flagellum. 99: 395-440.

• Bergeron JRC, Marlovits TC (2022). Cryo-EM of the injectisome and type III secretion systems. Curr. Opin. Strutc. Biol. 75: 102403

• Alphonse N, Wanford JJ, Voak AA, Gay J, Venkhaya S, Burroughs O, Mathew S, Lee T, Evans SL, Zhao W, Frowde K, Alrehaili A, Dickenson RE, Munk M, Panina S, Mahmood IF, Llorian M, Stanifer ML, Boulant S, Berchtold MW, Bergeron JRC, Wack A, Lesser CF, Odendall C. (2022) A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling. Cell 185 (13): 2354-2369.
  
  
• Mariano G, Faba-rodriguez R, Bui S, Zhao W, Ross J, Tsokov SB, Bergeron JRC (2022) Oligomerization of the FliF domains suggests a coordinated assembly of the flagellar MS ring. Frontiers in Microbiology, 12: 4107.
  

• Parker AV, Mann D, Tzokov SB, Hwang LC, Bergeron JRC (2021) The  structure of the bacterial DNA segregation ATPase filament reveals the conformational plasticity of ParA upon DNA binding. Nature Communications 12 (1): 5166.

• Mann D, Fan J, Somboon K, Farrell DP, Muenks A, Tzokov SB, DiMaio F, Khalid S, Miller SI, Bergeron JRC (2021) Structure and lipid dynamics in the maintenance of lipid asymmetry inner membrane complex of A. baumannii. Communications Biology, 4 (1): 817.
  

• Mariano G, Farthing RJ, Lale-Farjat SLM, Bergeron JRC (2020) Structural characterization of SARS-CoV-2: Where we are, and where we need to be. Frontiers  in Molecular Biosciences, 7:605236.
  

• Al-Otaibi NS, Bergeron JRC (2020) A new spin on flagellar rotation. Nature Microbiology, 5 (12): 1455-1456.

• Al-Otaibi NS, Taylor AJ, Farrell DP, Tzokov SB, DiMaio F, Kelly DJ, Bergeron JRC (2020) The cryo-EM structure of the bacterial flagellum cap complex suggests a molecular mechanism for filament elongation. Nature Communications 11 (1): 3210.

• Kamischke C, Fan J, Bergeron JRC, Kulasekara HD, Dalebroux ZD, Burrell A, Kollman JM, Miller SI (2019) The Acinetobacter baumannii Mla system and glycerophospholipid transport to the outer membrane. eLife, 8, pii:  e40171.

• Bergeron JRC, Brockerman JA, Vuckovic M, Deng W, Okon M, Finlay BB, McIntosh LP, Strynadka NCJ (2018) Characterization of the two conformations adopted by the T3SS inner-membrane protein PrgK. Protein Science, 27 (9): 1680-1691.

• Bergeron JRC, Hutto R, Ozyamak E, Hom N, Hansen J, Draper O, Byrne ME, Keyhani S, Komeili A & Kollman JM (2017) Structure of the magnetosome-associated actin-like MamK filament at subnanometer resolution. Protein Science, 26 (1): 93-102.
  


• Worrall LJ, Hong C, Vuckovic M, Deng W, Bergeron JRC, Majewski DD, Huang RK, Spreter T, Finlay BB, Yu Z & Strynadka NCJ (2016) Near-atomic-resolution cryo-EM analysis of the Salmonella T3S injectisome basal body. Nature, 540 (7634): 597-601.  


• Wong LH, Sinha S, Bergeron JR, Mellor JC, Giaever G, Flaherty P & Nislow C (2016) Reverse Chemical Genetics: Comprehensive Fitness Profiling Reveals the Spectrum of Drug Target Interactions. PLOS Genetics, 12 (9).
  


• Bergeron JRC, Fernández L, Wasney GA, Vuckovic M, Reffuveille F, Hancock REW & Strynadka NCJ (2016) The Structure of a Type 3 Secretion System (T3SS) Ruler Protein Suggests a Molecular Mechanism for Needle Length Sensing. Journal of Biological Chemistry, 291 (4): 1676-1691.  


• Bergeron JR (2016) Structural modeling of the flagellum MS ring protein FliF reveals similarities to the type III secretion system and sporulation complex. PeerJ, 4: e1718-e1718.  


• Dicks MDJ, Goujon C, Pollpeter D, Betancor G, Apolonia L, Bergeron JRC & Malim MH (2016) Oligomerization Requirements for MX2-Mediated Suppression of HIV-1 Infection. Journal of Virology, 90 (1): 22-32.  


• Solomonson M, Setiaputra D, Makepeace KAT, Lameignere E, Petrotchenko EV, Conrady DG, Bergeron JR, Vuckovic M, DiMaio F, Borchers CH, Yip CK & Strynadka NCJ (2015) Structure of EspB from the ESX-1 Type VII Secretion System and Insights into its Export Mechanism. Structure, 23(3), 571-583.  


• Bergeron JRC & Sgourakis NG (2015) Type IV Pilus: One Architectural Problem, Many Structural Solutions. Structure, 23(2), 253-255.  


• Bergeron JRC, Worrall LJ, De S, Sgourakis NG, Cheung AH, Lameignere E, Okon M, Wasney GA, Baker D, McIntosh LP & Strynadka NCJ (2015) The Modular Structure of the Inner-Membrane Ring Component PrgK Facilitates Assembly of the Type III Secretion System Basal Body. Structure, 23 (1): 161-172.  


• Lu Z, Bergeron JRC, Atkinson RA, Schaller T, Veselkov DA, Oregioni A, Yang Y, Matthews SJ, Malim MH & Sanderson MR (2013) Insight into the HIV-1 Vif SOCS-box-ElonginBC interaction. Open Biology, 3 (11): 130100-130100.  


• Bergeron JRC, Worrall LJ, Sgourakis NG, DiMaio F, Pfuetzner RA, Felise HB, Vuckovic M, Yu AC, Miller SI, Baker D & Strynadka NCJ (2013) A Refined Model of the Prototypical Salmonella SPI-1 T3SS Basal Body Reveals the Molecular Basis for Its Assembly. PLoS Pathogens, 9 (4): e1003307-e1003307.  


• Thanabalasuriar A, Bergeron J, Gillingham A, Mimee M, Thomassin J-L, Strynadka N, Kim J & Gruenheid S (2012) Sec24 interaction is essential for localization and virulence-associated function of the bacterial effector protein NleA. Cellular Microbiology, 14 (8): 1206-1218.  


• Sherer NM, Swanson CM, Hué S, Roberts RG, Bergeron JRC & Malim MH (2011) Evolution of a Species-Specific Determinant within Human CRM1 that Regulates the Post-transcriptional Phases of HIV-1 Replication. PLoS Pathogens, 7 (11):  e1002395-e1002395.  


• Lu D, Fillet S, Meng C, Alguel Y, Kloppsteck P, Bergeron J, Krell T, Gallegos M-T, Ramos J & Zhang X (2010) Crystal structure of TtgV in complex with its DNA operator reveals a general model for cooperative DNA binding of tetrameric gene regulators. Genes & Development, 24 (22): 2556-2565.  


• Ramboarina S, Garnett JA, Zhou M, Li Y, Peng Z, Taylor JD, Lee W-C, Bodey A, Murray JW, Alguel Y, Bergeron J, Bardiaux B, Sawyer E, Isaacson R, Tagliaferri C, Cota E, Nilges M, Simpson P, Ruiz T, Wu H & Matthews S (2010) Structural Insights into Serine-rich Fimbriae from Gram-positive Bacteria. Journal of Biological Chemistry, 285 (42): 32446-32457.  


• Autore F, Bergeron JRC, Malim MH, Fraternali F & Huthoff H (2010) Rationalisation of the Differences between APOBEC3G Structures from Crystallography and NMR Studies by Molecular Dynamics Simulations. PLoS ONE, 5 (7): e11515-e11515.  


• Bergeron JRC, Huthoff H, Veselkov DA, Beavil RL, Simpson PJ, Matthews SJ, Malim MH & Sanderson MR (2010) The SOCS-Box of HIV-1 Vif Interacts with ElonginBC by Induced-Folding to Recruit Its Cul5-Containing Ubiquitin Ligase Complex. PLoS Pathogens, 6 (6): e1000925-e1000925.  


• Carpenter EP, Corbett A, Thomson H, Adacha J, Jensen K, Bergeron J, Kasampalidis I, Exley R, Winterbotham M, Tang C, Baldwin GS & Freemont P (2007) AP endonuclease paralogues with distinct activities in DNA repair and bacterial pathogenesis. The EMBO Journal, 26 (5): 1363-1372.